C33Y (p.Cys33Tyr) variant of FAN1 (Fanconi-associated nuclease 1)
C33Y (p.Cys33Tyr) in FAN1 (Fanconi-associated nuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
C33Y (p.Cys33Tyr) variant details
- p.Cys33Tyr
- gnomAD 15-30904761-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.19
- CADD 7.39
- PolyPhen-2 0.00
- SIFT 0.31
- Population evidence available
- Structural context available
- Literature evidence available