A26V (p.Ala26Val) variant of FAN1 (Fanconi-associated nuclease 1)
A26V (p.Ala26Val) in FAN1 (Fanconi-associated nuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A26V (p.Ala26Val) variant details
- p.Ala26Val
- gnomAD rs1454061107
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.24
- CADD 5.11
- PolyPhen-2 0.05
- SIFT 0.36
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available