A26S (p.Ala26Ser) variant of FAN1 (Fanconi-associated nuclease 1)
A26S (p.Ala26Ser) in FAN1 (Fanconi-associated nuclease 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
A26S (p.Ala26Ser) variant details
- p.Ala26Ser
- gnomAD 15-30904732-G-GA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.263
- CADD 25.70
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available
- Literature evidence available