A26P (p.Ala26Pro) variant of FAN1 (Fanconi-associated nuclease 1)
A26P (p.Ala26Pro) in FAN1 (Fanconi-associated nuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A26P (p.Ala26Pro) variant details
- p.Ala26Pro
- ExAC rs758101202
- gnomAD rs758101202
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.25
- CADD 16.70
- PolyPhen-2 0.10
- SIFT 0.20
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available