T68S (p.Thr68Ser) variant of F8 (Coagulation factor VIII)
T68S (p.Thr68Ser) in F8 (Coagulation factor VIII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
T68S (p.Thr68Ser) variant details
- p.Thr68Ser
- Ensembl rs2124148989
- Missense
- Variant Prioritization Score for Impact Estimate 0.706
- REVEL 0.72
- MetaLR 0.92
- MetaSVM 0.89
- CADD 23.00
- PolyPhen-2 0.62
- SIFT 0.26
- Population evidence available
- Structural context available