T61A (p.Thr61Ala) variant of F8 (Coagulation factor VIII)
T61A (p.Thr61Ala) in F8 (Coagulation factor VIII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
T61A (p.Thr61Ala) variant details
- p.Thr61Ala
- rs1441828171
- gnomAD X-154882057-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- CADD 4.92
- SIFT 0.08
- Most common in the East Asian population (allele frequency 0.00035)
- Structural context available
- Literature evidence available