Q37K (p.Gln37Lys) variant of F8 (Coagulation factor VIII)
Q37K (p.Gln37Lys) in F8 (Coagulation factor VIII) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
Q37K (p.Gln37Lys) variant details
- p.Gln37Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.39
- MetaLR 0.79
- MetaSVM 0.24
- CADD 5.96
- PolyPhen-2 0.01
- SIFT 0.12
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available