T46S (p.Thr46Ser) variant of F2 (Prothrombin)
T46S (p.Thr46Ser) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
T46S (p.Thr46Ser) variant details
- p.Thr46Ser
- gnomAD 11-46719759-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.39
- CADD 1.95
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available