T46I (p.Thr46Ile) variant of F2 (Prothrombin)
T46I (p.Thr46Ile) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
T46I (p.Thr46Ile) variant details
- p.Thr46Ile
- cosmic curated COSV10814
- ExAC rs751494277
- gnomAD rs751494277
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.46
- CADD 14.80
- PolyPhen-2 0.08
- SIFT 0.04
- Population evidence available
- Structural context available