S36L (p.Ser36Leu) variant of F2 (Prothrombin)
S36L (p.Ser36Leu) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
S36L (p.Ser36Leu) variant details
- p.Ser36Leu
- ExAC rs764885504
- TOPMed rs764885504
- gnomAD rs764885504
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.49
- CADD 23.90
- PolyPhen-2 0.51
- SIFT 0.04
- Population evidence available
- Structural context available