P31L (p.Pro31Leu) variant of F2 (Prothrombin)
P31L (p.Pro31Leu) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
P31L (p.Pro31Leu) variant details
- p.Pro31Leu
- gnomAD 11-46719714-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.31
- CADD 21.10
- PolyPhen-2 0.08
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available