L38P (p.Leu38Pro) variant of F2 (Prothrombin)
L38P (p.Leu38Pro) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, published literature, and structural context.
L38P (p.Leu38Pro) variant details
- p.Leu38Pro
- gnomAD 11-46719735-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.809
- REVEL 0.91
- CADD 29.70
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available