L37P (p.Leu37Pro) variant of F2 (Prothrombin)
L37P (p.Leu37Pro) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
L37P (p.Leu37Pro) variant details
- p.Leu37Pro
- gnomAD 11-46719732-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.728
- REVEL 0.78
- CADD 29.20
- PolyPhen-2 0.93
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available