L37M (p.Leu37Met) variant of F2 (Prothrombin)
L37M (p.Leu37Met) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L37M (p.Leu37Met) variant details
- p.Leu37Met
- gnomAD 11-46719731-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.31
- CADD 17.50
- PolyPhen-2 0.21
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available