L15A (p.Leu15Ala) variant of F2 (Prothrombin)
L15A (p.Leu15Ala) in F2 (Prothrombin) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
L15A (p.Leu15Ala) variant details
- p.Leu15Ala
- gnomAD 11-46719275-G-GCT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.592
- CADD 24.50
- Population evidence available
- Structural context available
- Literature evidence available