H3Y (p.His3Tyr) variant of F2 (Prothrombin)
H3Y (p.His3Tyr) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
H3Y (p.His3Tyr) variant details
- p.His3Tyr
- ExAC rs773112047
- gnomAD rs773112047
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.33
- CADD 22.50
- PolyPhen-2 0.26
- SIFT 0.02
- Population evidence available
- Structural context available