G11D (p.Gly11Asp) variant of F2 (Prothrombin)
G11D (p.Gly11Asp) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
G11D (p.Gly11Asp) variant details
- p.Gly11Asp
- gnomAD 11-46719267-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- REVEL 0.60
- CADD 23.30
- PolyPhen-2 0.36
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available