F28L (p.Phe28Leu) variant of F2 (Prothrombin)
F28L (p.Phe28Leu) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data, published literature, and structural context.
F28L (p.Phe28Leu) variant details
- p.Phe28Leu
- gnomAD 11-46719706-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.802
- REVEL 0.81
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available