C19W (p.Cys19Trp) variant of F2 (Prothrombin)
C19W (p.Cys19Trp) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
C19W (p.Cys19Trp) variant details
- p.Cys19Trp
- gnomAD 11-46719292-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.37
- CADD 11.00
- PolyPhen-2 0.07
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available