A2T (p.Ala2Thr) variant of F2 (Prothrombin)
A2T (p.Ala2Thr) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
A2T (p.Ala2Thr) variant details
- p.Ala2Thr
- cosmic curated COSV61315
- gnomAD rs1195889853
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.34
- CADD 22.60
- PolyPhen-2 0.15
- SIFT 0.02
- Population evidence available
- Structural context available