A17P (p.Ala17Pro) variant of F2 (Prothrombin)
A17P (p.Ala17Pro) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
A17P (p.Ala17Pro) variant details
- p.Ala17Pro
- gnomAD 11-46719284-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.57
- CADD 12.60
- PolyPhen-2 0.09
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available