A14T (p.Ala14Thr) variant of F2 (Prothrombin)
A14T (p.Ala14Thr) in F2 (Prothrombin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
A14T (p.Ala14Thr) variant details
- p.Ala14Thr
- gnomAD 11-46719275-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.28
- CADD 19.20
- PolyPhen-2 0.08
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available