Y19C (p.Tyr19Cys) variant of F13B (Coagulation factor XIII B chain)
Y19C (p.Tyr19Cys) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
Y19C (p.Tyr19Cys) variant details
- p.Tyr19Cys
- ExAC rs780445814
- TOPMed rs780445814
- gnomAD rs780445814
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.13
- CADD 7.70
- PolyPhen-2 0.43
- SIFT 0.09
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available