Y108F (p.Tyr108Phe) variant of F13B (Coagulation factor XIII B chain)
Y108F (p.Tyr108Phe) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Y108F (p.Tyr108Phe) variant details
- p.Tyr108Phe
- ExAC rs759690063
- TOPMed rs759690063
- gnomAD rs759690063
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.22
- CADD 19.20
- PolyPhen-2 0.45
- SIFT 0.75
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available