T64I (p.Thr64Ile) variant of F13B (Coagulation factor XIII B chain)
T64I (p.Thr64Ile) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
T64I (p.Thr64Ile) variant details
- p.Thr64Ile
- ExAC rs749334266
- TOPMed rs749334266
- gnomAD rs749334266
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.39
- CADD 24.30
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available