T124A (p.Thr124Ala) variant of F13B (Coagulation factor XIII B chain)
T124A (p.Thr124Ala) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
T124A (p.Thr124Ala) variant details
- p.Thr124Ala
- ExAC rs779600903
- TOPMed rs779600903
- gnomAD rs779600903
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- REVEL 0.28
- CADD 23.50
- PolyPhen-2 0.94
- SIFT 0.05
- Most common in the South Asian population (allele frequency 0.00013)
- Structural context available