R86S (p.Arg86Ser) variant of F13B (Coagulation factor XIII B chain)
R86S (p.Arg86Ser) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R86S (p.Arg86Ser) variant details
- p.Arg86Ser
- TOPMed rs956705006
- gnomAD rs956705006
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.10
- CADD 17.10
- PolyPhen-2 0.26
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available