P85S (p.Pro85Ser) variant of F13B (Coagulation factor XIII B chain)
P85S (p.Pro85Ser) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
P85S (p.Pro85Ser) variant details
- p.Pro85Ser
- TOPMed rs1655914715
- Missense
- Variant Prioritization Score for Impact Estimate 0.629
- REVEL 0.59
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available