M114L (p.Met114Leu) variant of F13B (Coagulation factor XIII B chain)
M114L (p.Met114Leu) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
M114L (p.Met114Leu) variant details
- p.Met114Leu
- ExAC rs771577237
- gnomAD rs771577237
- Missense
- Variant Prioritization Score for Impact Estimate 0.0523
- REVEL 0.03
- CADD 0.01
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available