M114K (p.Met114Lys) variant of F13B (Coagulation factor XIII B chain)
M114K (p.Met114Lys) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
M114K (p.Met114Lys) variant details
- p.Met114Lys
- gnomAD rs1301354226
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.38
- CADD 23.00
- PolyPhen-2 0.58
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available