L106S (p.Leu106Ser) variant of F13B (Coagulation factor XIII B chain)
L106S (p.Leu106Ser) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
L106S (p.Leu106Ser) variant details
- p.Leu106Ser
- TOPMed rs1655877201
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.20
- CADD 14.20
- PolyPhen-2 0.34
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available