L106F (p.Leu106Phe) variant of F13B (Coagulation factor XIII B chain)
L106F (p.Leu106Phe) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L106F (p.Leu106Phe) variant details
- p.Leu106Phe
- TOPMed rs903500003
- gnomAD rs903500003
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.19
- CADD 2.66
- PolyPhen-2 0.55
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)
- Structural context available