K23Q (p.Lys23Gln) variant of F13B (Coagulation factor XIII B chain)
K23Q (p.Lys23Gln) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K23Q (p.Lys23Gln) variant details
- p.Lys23Gln
- TOPMed rs1047178726
- gnomAD rs1047178726
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.08
- CADD 25.10
- PolyPhen-2 0.84
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available