I51T (p.Ile51Thr) variant of F13B (Coagulation factor XIII B chain)
I51T (p.Ile51Thr) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I51T (p.Ile51Thr) variant details
- p.Ile51Thr
- ExAC rs766202207
- TOPMed rs766202207
- gnomAD rs766202207
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.14
- CADD 14.00
- PolyPhen-2 0.06
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available