I11T (p.Ile11Thr) variant of F13B (Coagulation factor XIII B chain)
I11T (p.Ile11Thr) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
I11T (p.Ile11Thr) variant details
- p.Ile11Thr
- ExAC rs755472323
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.12
- CADD 21.20
- PolyPhen-2 0.11
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available