C91F (p.Cys91Phe) variant of F13B (Coagulation factor XIII B chain)
C91F (p.Cys91Phe) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
C91F (p.Cys91Phe) variant details
- p.Cys91Phe
- ExAC rs753737260
- TOPMed rs753737260
- gnomAD rs753737260
- Missense
- Variant Prioritization Score for Impact Estimate 0.828
- REVEL 0.87
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available