C59W (p.Cys59Trp) variant of F13B (Coagulation factor XIII B chain)
C59W (p.Cys59Trp) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
C59W (p.Cys59Trp) variant details
- p.Cys59Trp
- ExAC rs774579966
- gnomAD rs774579966
- Missense
- Variant Prioritization Score for Impact Estimate 0.605
- REVEL 0.81
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available