A61G (p.Ala61Gly) variant of F13B (Coagulation factor XIII B chain)
A61G (p.Ala61Gly) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A61G (p.Ala61Gly) variant details
- p.Ala61Gly
- TOPMed rs1447128343
- gnomAD rs1447128343
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.20
- CADD 25.00
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available