A20T (p.Ala20Thr) variant of F13B (Coagulation factor XIII B chain)
A20T (p.Ala20Thr) in F13B (Coagulation factor XIII B chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A20T (p.Ala20Thr) variant details
- p.Ala20Thr
- ExAC rs756460140
- TOPMed rs756460140
- gnomAD rs756460140
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.13
- CADD 24.20
- PolyPhen-2 0.64
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available