Y31H (p.Tyr31His) variant of F12 (Coagulation factor XII)
Y31H (p.Tyr31His) in F12 (Coagulation factor XII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
Y31H (p.Tyr31His) variant details
- p.Tyr31His
- gnomAD rs1258809696
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.19
- CADD 0.21
- PolyPhen-2 0.00
- SIFT 0.81
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available