W85R (p.Trp85Arg) variant of F12 (Coagulation factor XII)
W85R (p.Trp85Arg) in F12 (Coagulation factor XII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
W85R (p.Trp85Arg) variant details
- p.Trp85Arg
- Ensembl rs1763275374
- Missense
- Variant Prioritization Score for Impact Estimate 0.556
- REVEL 0.51
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available