W85* (p.Trp85Ter) variant of F12 (Coagulation factor XII)
W85* (p.Trp85Ter) in F12 (Coagulation factor XII) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
W85* (p.Trp85Ter) variant details
- p.Trp85Ter
- ESP rs370954285
- ExAC rs370954285
- TOPMed rs370954285
- gnomAD rs370954285
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.736
- CADD 35.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available