P67R (p.Pro67Arg) variant of F12 (Coagulation factor XII)
P67R (p.Pro67Arg) in F12 (Coagulation factor XII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P67R (p.Pro67Arg) variant details
- p.Pro67Arg
- Ensembl rs2127361099
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.07
- CADD 18.20
- PolyPhen-2 0.05
- SIFT 0.11
- Most common in the HGDP:ADYGEI population (allele frequency 0.029)
- Structural context available