P26S (p.Pro26Ser) variant of F12 (Coagulation factor XII)
P26S (p.Pro26Ser) in F12 (Coagulation factor XII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P26S (p.Pro26Ser) variant details
- p.Pro26Ser
- gnomAD rs1443190474
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.11
- CADD 14.20
- PolyPhen-2 0.02
- SIFT 0.12
- Most common in the Ashkenazi Jewish population (allele frequency 7.9e-05)
- Structural context available