G108R (p.Gly108Arg) variant of F12 (Coagulation factor XII)
G108R (p.Gly108Arg) in F12 (Coagulation factor XII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
G108R (p.Gly108Arg) variant details
- p.Gly108Arg
- TOPMed rs1362829054
- gnomAD rs1362829054
- Missense
- Variant Prioritization Score for Impact Estimate 0.723
- REVEL 0.71
- CADD 23.40
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available