F9L (p.Phe9Leu) variant of F12 (Coagulation factor XII)
F9L (p.Phe9Leu) in F12 (Coagulation factor XII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F9L (p.Phe9Leu) variant details
- p.Phe9Leu
- ExAC rs755227896
- TOPMed rs755227896
- gnomAD rs755227896
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.10
- CADD 16.70
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available