A25D (p.Ala25Asp) variant of F12 (Coagulation factor XII)
A25D (p.Ala25Asp) in F12 (Coagulation factor XII) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
A25D (p.Ala25Asp) variant details
- p.Ala25Asp
- TOPMed rs926232985
- gnomAD rs926232985
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.17
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available