P115L (p.Pro115Leu) variant of EZH2 (Q15910)
P115L (p.Pro115Leu) in EZH2 (Q15910) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
P115L (p.Pro115Leu) variant details
- p.Pro115Leu
- cosmic curated COSV10733
- Missense
- Variant Prioritization Score for Impact Estimate 0.803
- REVEL 0.82
- CADD 27.00
- PolyPhen-2 0.47
- SIFT 0.00
- Population evidence available
- Structural context available