L98S (p.Leu98Ser) variant of EZH2 (Q15910)
L98S (p.Leu98Ser) in EZH2 (Q15910) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
L98S (p.Leu98Ser) variant details
- p.Leu98Ser
- cosmic curated COSV57446
- Missense
- Variant Prioritization Score for Impact Estimate 0.725
- REVEL 0.78
- CADD 26.80
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available