G144D (p.Gly144Asp) variant of ETV4 (ETS translocation variant 4)
G144D (p.Gly144Asp) in ETV4 (ETS translocation variant 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data.
G144D (p.Gly144Asp) variant details
- p.Gly144Asp
- rs780292322
- NCI-TCGA Cosmic COSV1000
- cosmic curated COSV10008
- ExAC rs780292322
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.10
- CADD 21.40
- PolyPhen-2 0.37
- SIFT 0.15
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)